There are probably more busking tricks than there are people in this forum but a, non-exhaustive, list might include...
Only use playbacks for the intensities of fixture groups, do the rest in the programmer. Practically limitless but difficult to keep track. Look up programmer time if you go down this route.
Whether using the programmer or not, use palletes for LED colours, positions, beam & shape. Much easier to amend and makes them easy to apply when busking in the programmer.
Record cue stacks and use go cue no. (hold the go button, type cue no. - on an external keyboard since it is S series - release the go button). Economical with playbacks but looking up the cue no. takes time does mean you can go from one cue directly to the next. It's in the manual with S48 selected but the text only refers to FLX so not sure it works @Edward Z88 will advise I'm sure.
Use colour mixing for LEDs. Always a good choice but don't try to use playbacks or programmer for LED colours if you've set up colour mixing.
Don't record full "looks", instead for (e.g) moving heads have some beam, shape, position & effect options on different playbacks so you can mix & match.
Don't forget you can have playbacks that control a single parameter (like pan, tilt, zoom, etc.).
Get into OSC sooner rather than later. I used to use midi (on FLX) but OSC is more flexible, uses less playbacks and available on S series. If you want more help with OSC contact me by DM.
There are remote switches on FLX but these can also be triggered by ctrl/F1 to ctrl/F8 on the keyboard. These don't appear in the S48 manual so not sure if you have them or not. Again @Edward Z88 will advise.
All I can think of quickly but I'm sure you will get other's offering their take on the subject.
My own set up uses 18 playbacks as follows...
1 thru 6 contain cues setting LED PARs fixtures grouped by location and odd/even to one of 13 colours.
7 is the same 13 colours but for a small number of LED moving head washes. 8 thru 10 are positions, zoom settings and P/T effects for these mh washes.
11 is colour wheel settings for DS (non LED) moving heads, 12, 13 & 14 positions, gobo & P/T effects for these fixtures.
15 thru 18 are the colours, gobos, positions & effects US non LED mh's
On another page I have the intensities for all the above fixtures, grouped similarly and a few LED colour effects like rainbow and sparkle.
Finally, a tablet running TouchOSC (full one, not MK1) and a control surface I designed and coded myself to trigger the cues. This is customisable and I am willing to share it with a few people (because I couldn't support a big userbase). I'd have to write a user manual though.
Have fun!